Image 1 (IMAGE) Nara Institute of Science and Technology Caption Tumor cells were treated with curcumin (50 μM) and PGV-1 (0.8 μM) for 24 hr, and then subjected to Mitotic spread assay (upper panels) and Giemsa staining (lower panels). PGV-1 treatment markedly arrested tumor cells in the prometaphase stage (M phase) of the cell cycle. Credit Jun-ya Kato Usage Restrictions Credit required. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.