Reality Check for DNA Nanotechnology (IMAGE)

Technical University of Munich (TUM)

Reality Check for DNA Nanotechnology

Caption

This 3-D print shows a DNA-based structure designed to test a critical assumption -- that such objects could be realized, as designed, with subnanometer precision. This object is a relatively large, three-dimensional DNA-based structure, asymmetrical to help determine the orientation, and incorporating distinctive design motifs. Subnanometer-resolution imaging with low-temperature electron microscopy enabled researchers to map the object -- which comprises more than 460,000 atoms -- with subnanometer-scale detail.

Credit

Dietz Lab, TU Muenchen

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