Structure of anti-CRISPR Protein Bound to Cas9 (IMAGE)

University of California - Berkeley

Structure of anti-CRISPR Protein Bound to Cas9

Caption

The anti-CRISPR protein (red on right) mimics DNA, binding in the site where the cutting enzyme Cas9 typically grips the target DNA (left) before it cuts. But the anti-CRISPR protein doesn't let go, essentially killing Cas9's gene editing ability.

Credit

Fuguo Jiang, UC Berkeley

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