Vicious Cycle in Critical Illness (IMAGE) Michigan Medicine - University of Michigan Caption The new findings suggest that a cycle of microbiome disruption, inflammation and tissue injury may be involved in critical illness involving the lungs. Credit University of Michigan Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.