Frontotemporal Dementia in a Dish (IMAGE)
Caption
Mount Sinai researchers were able to recreate much of the damage seen in a widely-studied form of frontotemporal dementia by growing special types of cerebral organoids in petri dishes. Experiments on the organoids showed disease-causing mutations in a protein called tau may trigger a cascade of molecular events that led to the death of a specific class of neurons known to be vulnerable in frontotemporal dementia.
Credit
Courtesy of the Goate lab, Mount Sinai, N.Y., N.Y.
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