Katie Alexander (IMAGE)

University of Alabama at Birmingham

Katie Alexander

Caption

Last year, researchers used a mouse model that included immune-reactive T cells from patients with Crohn's disease in a proof-of-principle demonstration that a flagellin-directed immunotherapy might provide similar benefits in patients. Now they have moved a step closer to possible clinical testing of this treatment, with a study, published in the journal Gastroenterology, that is the first to describe IgG antibodies in Crohn's disease specific for human-derived flagellins of bacteria in the Lachnospiraceae family.

Credit

UAB

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.