Myoblast Fusion (IMAGE)

NIH/National Human Genome Research Institute

Myoblast Fusion

Caption

The graphic depicts normal myoblasts (early muscle cells with a single nucleus) fusing together to form muscle cells with more than one nucleus. The cascade is disrupted in Carey-Fineman-Ziter syndrome, because of a defect in the membrane protein, myomaker, which is required for cell-cell fusion

Credit

Darryl Leja, NHGRI

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