Healthy Motor Neuron Vs. SMA Motor Neuron (IMAGE)

Columbia University Irving Medical Center

Healthy Motor Neuron Vs. SMA Motor Neuron

Caption

Spinal motor neurons (blue) affected by SMA (right image) have significantly less expression of Kv2.1 potassium channel (yellow), decreasing their ability to fire (recordings on the top right of each image).

Credit

Source: Lab of George Z. Mentis, PhD, Columbia University Medical Center

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