Hypnozoite: Serological Markers for Detecting Dormant Plasmodium Vivax Infection (IMAGE)

Ehime University

Hypnozoite: Serological Markers for Detecting Dormant Plasmodium Vivax Infection

Caption

(A) How to detect dormant hypnozoite of P. vivax? Antibodies can predict recent infections if they have the correct kinetic profile (Green line, serological marker of hypnozoite). Antigens selected based on the kinetic profiles in 9 months following clearance of infection are candidates for detecting hypnozoites. (B) Hypnozoite biomarkers. Eight antibody responses classified P. vivax infections in the previous 9 months with 80% sensitivity & specificity.

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Ehime University

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