Skin Nevus (IMAGE) Houston Methodist Caption The mutation BrafV600E is found in 70 percent or more of benign birthmarks and moles in humans. Scientists believe the Braf mutation alone isn't enough to cause cancer. A variety of subsequent mutations identified in the present study, however, make melanomas possible. Credit Houston Methodist Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.