(IMAGE) McGill University Health Centre Caption This is a computer image of a head in nuclear magnetic resonance (NMR), a technique at the root of clinical diagnosis for leukodystrophies. Here, the brain is replaced by the 3D structure of an RNA polymerase, the enzyme targeted by mutations in POLR1C. Credit Dr. Benoit Coulombe (IRCM) Usage Restrictions Credit Dr. Benoit Coulombe (IRCM) License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.