Developing Fish Spines (IMAGE) Duke University Caption A single-letter DNA change in a gene that lays down the pattern for a developing spine in zebrafish caused mutant fish to develop backbones that resemble ancestral fish (bottom image). Credit Michel Bagnat Lab, Duke University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.