Study Raises Safety Concerns about Anti-Notch Therapy for Cancer (IMAGE)

WashU Medicine

Study Raises Safety Concerns about Anti-Notch Therapy for Cancer

Caption

When Washington University scientists disrupted Notch1 signaling in mice, they developed vascular tumors, primarily in the liver, which filled with blood (shown) and eventually led to massive hemorrhages and death.

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Washington University in St. Louis

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