Genomic Safe Harbors (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

Genomic Safe Harbors

Caption

A collaborative research team at Harvard’s Wyss Institute and the ETH Zurich in Switzerland has identified genomic safe harbors (GSHs) in the tumultuous see of human genome sequence to land therapeutic genes in. As part of their validation, they inserted a fluorescent GFP reporter gene into candidate GSHs and followed its expression over time. The GSHs could enable safer and longer-lasting expression of genes in future gene and cellular therapies. This illustration won the team the cover of the Cell Reports Methods issue the study is published in.

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Erik Aznauryan

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