Research framework and main findings of T cell atlas (IMAGE)

Peking University

Research framework and main findings of T cell atlas

Caption

Systematic analysis of a human pan-cancer T cell atlas.We analyzed approximately 390,000 T cells from 316 patients of 21 cancer types by means of scRNA-seq. Combining gene expression profiles and T cell receptor sequences, we investigated the heterogeneity and dynamics of tumor-infiltrating T cells and performed a systematic comparison of T cells among cancer types. Additionally, we provided a T cell composition–based immune-typing scheme. KIR, killer cell immunoglobulin-like receptor; IL26, interleukin-26.

Credit

Peking University Cancer Hospital and Institute

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