New MRI Technique Detects MS Brain Changes Earlier (IMAGE)

Radiological Society of North America

New MRI Technique Detects MS Brain Changes Earlier

Caption

(A, B) Sample spectra and abnormal metabolic images of myo-inositol (mI), N-acetylaspartate (NAA), and the ratio of mI to NAA (mI/NAA) together with MRI scans in two participants with multiple sclerosis. Red arrow in A indicates region in normal-appearing white matter with higher signal intensity of mI only. Yellow arrow in B indicates region with higher signal intensity of mI and reduced signal intensity of NAA, where no changes or only diffuse changes are visible at T1-weighted MRI (T1w)/ fluid-attenuated inversion-recovery (FLAIR) imaging, and green arrow indicates white matter lesions, where elevated mI signal intensity extends FLAIR-visible pathologic findings. i.u. = institutional unit, ppm = parts per million, tCho = total choline, tCr = total creatine.

Credit

Radiological Society of North America

Usage Restrictions

May use with credit.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.