UGDH manipulation regulates concentration dependence of enzalutamide growth suppression (IMAGE)
Caption
Figure 7: UGDH manipulation regulates concentration dependence of enzalutamide growth suppression. (A and B) LNCaP AD cells overexpressing UGDH (B) were compared to vector control (A) and to LNCaP CR cells with UGDH knocked down (C, Control; D, UGDH KD). Equal cell numbers were plated and treated for three days with the indicated concentrations of enzalutamide (in mM). Proliferating cells were quantified in a fluorescence plate reader using resazurin-resorufin conversion. Daily cell count was determined from a standard curve and represents the mean of four technical replicates ± SEM; *p < 0.05.
Credit
Correspondence to - Melanie A. Simpson - msimpso3@ncsu.edu
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CC BY