Microenvironment at the initiation stage of breast cancer carcinogenesis generated by FRS2β. (IMAGE)

Kanazawa University

Microenvironment at the initiation stage of breast cancer carcinogenesis generated by FRS2β.

Caption

Cancer stem cells emerging in the initial microenvironment of the mammary gland of the breast cancer mouse model MMTV-ErbB2 proliferate to form a tumor mass (left). On the other hand, MMTV-ErbB2/Frs2β -/- mammary glands lacking FRS2β do not form such an initial microenvironment and even when cancer stem cells emerge, they do not proliferate.

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Kanazawa University

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