3D culture of OSCC (IMAGE) Niigata University Caption A 3D culture of OSCC cells with cancer-associated fibrosis (CAF) or normal oral fibroblasts (NOF). Hematoxylin and eosin (H&E) staining of a 3D cancer model consisting of an OSCC cell line seeded in acellular stromal layers or embedded in CAF or NOF. Immunohistochemical staining of SOX9 in 3D cancer-NOF models or 3D cancer-CAF models. Credit Niigata University Usage Restrictions The image may only be used with appropriate caption or credit. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.