Figure 1 (IMAGE)
Caption
1. Scheme of the patient-specific computational workflow to predict the risk of device-related thrombus (DRT) formation after left atrial appendage occluder (LAAO) implantation. A: computerized tomography (CT) scan acquisition of whole left atrium (LA) and ultrasound (US) study with Doppler measurements at mitral valve (MV) level. B: 3D LA segmentation and model generation where finite volume analysis was performed. C: blood flow velocities and in silico indices like endothelial cell activation potential (ECAP) estimated from personalized computational fluid dynamics simulations. D: the risk factors predicting the presence of DRT were low velocities (< 0.20 m/s), and stagnated flow next to the device surface as well as high ECAP values (indicative of complex blood flow patterns and low wall shear stress).
Credit
2019 Sociedad Española de Cardiología. Published by Permanyer Publications
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