Supernova: a deoxyribozyme that catalyzes a chemiluminescent reaction (IMAGE)

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague)

Supernova: a deoxyribozyme that catalyzes a chemiluminescent reaction

Caption

Researchers from IOCB Prague used artificial evolution to identify a light-producing deoxyribozyme called Supernova. This catalyzes a chemiluminescent reaction in the presence of the 1,2-dioxetane substrate CDP-Star. Light production can also be coupled to ligand binding, suggesting that Supernova will be a useful addition to the toolkit of functional DNA parts. Original paper: https://doi.org/10.1002/anie.202109347.

Credit

Katerina Svehlova, Edward Curtis Group / IOCB Prague.

Usage Restrictions

Use with the credit and caption.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.