Design and construction of artificial protein nanoparticle TIP60 (IMAGE)

Shinshu University

Design and construction of artificial protein nanoparticle TIP60

Caption

Sixty fusion proteins of a pentameric Sm-like protein (PDB ID: 3BY7) and a dimeric MyoX-coil domain (PDB ID: 2LW9) self-assemble into a protein nanoparticle complex, TIP60 (Truncated Icosahedral Protein composed of 60-mer fusion proteins).

Credit

Reproduced from Icosahedral 60-meric porous structure of designed supramolecular protein nanoparticle TIP60, Ryoichi Arai et al., Chem. Commun., 2021, with permission from the Royal Society of Chemistry.

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