The result overviews (IMAGE) Tokyo Metropolitan Institute of Medical Science Caption The results of this study are summarized (A-B). Among 277 drug-naïve adolescents, 13 (4.7%) were assessed as persistent psychotic symptoms. Among the rest of the sample, 199 (71.8 %) and 65 (23.5 %) participants had no psychotic symptoms and transient psychotic symptoms, respectively (A). Multinomial logistic regression analysis adjusted for age and sex demonstrated that ORs for persistent and transient psychotic symptoms compared with those for no psychotic symptoms were 1.78 (95% CI, 1.14–2.76, P = 0.011) and 1.05 (95% CI, 0.79–1.40, P = 0.73), respectively, for a 1 SD increase in fingertip AGEs. The significance and magnitude of effect size for persistent psychotic symptoms remained even after excluding five participants who were using antipsychotic medications (OR, 1.68; 95% CI, 1.05–2.69; P = 0.03) (B). Error bars indicate the 95% confidence interval. Credit TMIMS Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.