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A team led by researchers at Massachusetts General Hospital (MGH) has generated premature cells that support early heart development but vanish soon after birth. These cells, called pre-epicardial cells, when cultured along with immature heart muscle cells, produce cells closer to mature heart muscle, seen beating gently here. The investigators hope that the advance, which is described in Nature Communications, will help bring them closer to achieving their goal of using patients’ cells to generate functioning heart tissue that could be transplanted, similar to donor organs, for the treatment of heart failure.
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Courtesy Harald C. Ott, MD
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