Graphical Abstract (IMAGE) AlphaMed Press Caption Mesenchymal stromal cells (MSCs) are potent immunomodulators that have shown promise in treating chronic obstructive pulmonary disease (COPD). Using transcriptomics, researchers have demonstrated that MSC infusions elicit a strong, yet transient (<7 days) transcriptional response in circulating mononuclear cells of COPD patients, attenuating key pro-inflammatory pathways. These responses are likely mediated by soluble factors and/or products of MSC breakdown. Credit AlphaMed Press Usage Restrictions none License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.