Figure 6 (IMAGE) Impact Journals LLC Caption Alteration in biomechanical properties of PANC-1 cells exposed to 5 μM cytochalasin D (CytD) in normoxia and hypoxia. (A) Time trace of Young's modulus E in normoxia (n = 5) and hypoxia (n = 5) after exposure to cytochalasin D. (B) Normalized values of cellular height, roughness, and adhesion measured after exposure to cytochalasin D in normoxia for 60 minutes (n = 5) and hypoxia for 90 minutes (n = 5). Data are mean ± s.d., Repeated measured one-way ANOVA, post-hoc Tukey test; ns, not significant; *P < 0.05; **P < 0.01; ****P < 0.0001. Statistics between normoxia and hypoxia showed no statistical difference (ns). Credit Correspondence to - Yongki Choi - yongki.choi@ndsu.edu Usage Restrictions Copyright: © 2021 Alhalhooly et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.