Figure 5 (IMAGE)

Impact Journals LLC

Figure 5

Caption

The prevalence of type 2 diabetes in m.1382A>C polymorphism carriers. (A) Forest plot for meta-analysis (pooled random effects) on the prevalence of type 2 diabetes in males. Odds ratios are adjusted by age and BMI. Test for the pooled effect, Z = 2.86, p < 0.01. Heterogeneity was insignificant (I2 = 0%, p = 0.84). (B) Forest plot for meta-analysis (pooled random effects) on the prevalence of type 2 diabetes in female. Odds ratios are adjusted by age and BMI. Test for the pooled effect, Z = -0.46, p = 0.64. Heterogeneity was insignificant (I2 = 33.6%, p = 0.22). In Japan Multi-Institutional Collaborative Cohort (J-MICC) study, m.1382A>C polymorphism carriers divided by tertile of physical activity in (C) males and (D) females. Activity was assessed by the degree of moderate-to-vigorous intensity physical activity (MVPA). In men only, sedentary levels of MVPA were associated with an increased risk of diabetes in the C allele. Cochran-Armitage trend test of m.1382 C allele for men, &chi;2 = 6.26, p = 0.012. Cochran-Armitage trend test of m.1382 A allele for females, &chi;2 = 0.03, p = 0.861.

Credit

Correspondence to: Noriyuki Fuku email: noriyuki.fuku@nifty.com and Pinchas Cohen email: hassy@usc.edu

Usage Restrictions

Copyright: © 2021 Zempo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.