Anti-rejection therapy (IMAGE) Johns Hopkins Medicine Caption Johns Hopkins Medicine and NCI Frederick researchers have demonstrated in mice that they can easily deliver a promising anti-rejection therapy directly to a transplanted heart by packaging it within a tiny protein gel cocoon known as a hydrogel. The steps in constructing the hydrogel and encapsulating the drug, tofacitinib, are illustrated in this graphic. The inset in the upper right is an actual photomicrograph of the tofacitinib crystals in place Credit Graphic created by M.E. Newman, Johns Hopkins Medicine, using an original illustration by Poulami Majumder and tofactinib molecular model courtesy of the National Center for Biotechnology Information Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.