Designer Estrogen May Offer Safer Alternative to Hormone Therapy (IMAGE)

American Association for the Advancement of Science (AAAS)

Designer Estrogen May Offer Safer Alternative to Hormone Therapy

Caption

A structural model of the estrogen receptor ERα bound to synthetic estrogen (PaPE-1) in comparison to natural estrogen (estradiol E2). This material relates to a paper that appeared in the May 24, 2016, issue of Science Signaling, published by AAAS. The paper, by Z. Madak-Erdogan at University of Illinois at Urbana-Champaign in Urbana, IL, and colleagues was titled, 'Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues.'

Credit

Z. Madak-Erdogan <i>et al. / Science Signaling</i> (2016)

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