Alpha Syn-Nuclein (IMAGE) Arizona State University Caption Brain image from the Substantia nigra in Parkinson's disease, showing alpha-synuclein, a key protein implicated in the disease. Positive staining (brown) indicates an intraneural Lewy-body. Credit Marvin 101 Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.