Schematic Representation of the Experimental Approach (IMAGE)
Caption
Schematic representation of the experimental approach adopted by the researchers. After 'probing' the structure of the SARS-CoV-2 RNA genome using specific chemical compounds, the secondary structure of stable RNA elements throughout the viral genome has been determined. Using this information, the 3D model of these RNA structure elements has been computationally determined, allowing the identification of potential pockets that might provide targets for the development of antiviral therapeutic strategies.
Credit
Danny Incarnato, University of Groningen
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