Hypoxia-Inducible Factor-1α (IMAGE) Neural Regeneration Research Caption Amplified bands of hypoxia-inducible factor-1α and heme oxygenase-1 mRNA appeared in the frontal cortex of chronic cerebral ischemic rats at three, six, and nine weeks. Cilostazol reduced hypoxia-inducible factor-1α and heme oxygenase-1 expression and activity. Credit <i>Neural Regeneration Research</i> Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.