Image of two cells overproducing the ClC-6 transporter (red) carrying the disease-causing mutation. (IMAGE)

Forschungsverbund Berlin

Image of two cells overproducing the ClC-6 transporter (red) carrying the disease-causing mutation.

Caption

This leads to the appearance of large vesicles that are positive for the lysosomal marker protein LAMP-1 (shown in green). Vesicles with high levels of both proteins appear yellow.

Credit

Carlo Barbini

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