CRISPR Gene Editing Tackles Sickle Cell Disease (2 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

CRISPR Gene Editing Tackles Sickle Cell Disease (2 of 2)

Caption

Researchers have exploited the CRISPR/Cas9 gene editing technique to correct the disease causing mutation in hematopoietic stem cells from patients with sickle cell disease, successfully engrafting these cells in mice. This material relates to a paper that appeared in the Oct. 12, 2016, issue of Science Translational Medicine, published by AAAS. The paper, by M.A. DeWitt at University of California - Berkeley in Berkeley, CA, and colleagues was titled, "Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells."

Credit

Val Altounian /<i>Science Translational Medicine</i> (2016)

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