Figure 2. Frankenbody Binds HA-tag in vivo (IMAGE)

_Tokyo Institute of Technology

Figure 2. Frankenbody Binds HA-tag in vivo

Caption

This wildtype anti-HA scFv does not fold properly in the reduced intracellular environment, and therefore displays little affinity for HA epitopes in living cells. However, both nuclear and cytoplasmic HA-tagged proteins can be labeled by the HA frankenbody in living cells.

Credit

Hiroshi Kimura, Timothy J. Stasevich

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