Illustration of Nervous System Injury (IMAGE)

Society for Neuroscience

Illustration of Nervous System Injury

Caption

Proposed model for the role of the blood protein fibrinogen that triggers scar formation in the brain and spinal cord. Fibrinogen carries an inactive substance called TGF-B, which circulates in the bloodstream of an uninjured nervous system (left panel). When there’s an injury and blood vessels leak, TGF-B interacts with local brain cells and sends signals that result in scar formation (right panel).

Credit

Courtesy, with permission: Schachtrup et al. The Journal of Neuroscience 2010.

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For reporters, free use with appropriate credit line. All others, please contact The Journal of Neuroscience.

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