Mutations across the genome add up to blood cancer risk in three popular dog breeds (IMAGE)

PLOS

Mutations across the genome add up to blood cancer risk in three popular dog breeds

Caption

Bernese mountain dogs present a high incidence of familial cancers: histiocytic sarcoma (in black), lymphoma (in blue), and mast cell tumor (in green). This breed represents a unique model to unravel the genetics of the corresponding human cancers, owing to strong cancer predispositions, due to founder effects and artificial selection applied by humans on dog breeds. Picture taken by Chantal Orellou.

Credit

Hédan B et al., 2021, PLOS Genetics

Usage Restrictions

CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.