Efflux Pumps (IMAGE)

DOE/Los Alamos National Laboratory

Efflux Pumps

Caption

Bacterial efflux pumps, such as the P. aeruginosa MexAB-OprM pump shown here, are one of the dominant molecular mechanisms available to Gram-negative pathogens for removing toxins, including antibiotics. Inactivation of the pump assembly and function would be a major step for reducing bacterial multidrug resistance.

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LANL

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