AIRE Mutations (IMAGE) Cell Press Caption The image illustrates how the mutated AIRE allele leads to autoimmune disease in human patients bearing the dominant mutations. Credit Image by Christian Bakke, Jakub Abramson and Bergithe E. Oftedal. Usage Restrictions Credit Required. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.