Atomic Model of the Complement Protein C4 (Brown) Trapped in the Complex with the Protein-Degrading (IMAGE)

Aarhus University

Atomic Model of the Complement Protein C4 (Brown) Trapped in the Complex with the Protein-Degrading

Caption

The model shows how the MASP-2 attaches itself to the C4, which allows the MASP-2 to cleave a small portion of the C4. This makes the structure of C4 change, which enables the C4 to bind to the surface of pathogenic microorganisms, for example, or our own dying cells

Credit

Rune T. Kidmose

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