Various Modes of Cancer Evolution (IMAGE)

The Institute of Medical Science, The University of Tokyo

Various Modes of Cancer Evolution

Caption

A-D) Four main evolutionary modes in cancer. Red stars represent normal driver mutations such as single nucleotide mutations. A green star represents large-scale genetic alterations at the chromosomal or genomic level that produce copy number or structural abnormalities. E) An evolutionary model that explains the temporal shift of the principle generating ITH during colorectal tumorigenesis.

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© 2020 IMSUT, The University of Tokyo CC-BY

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