Engram Cells in 9-Month-Old AD Mouse with Plaques (IMAGE)

RIKEN

Engram Cells in 9-Month-Old AD Mouse with Plaques

Caption

This image represents a coronal section of hippocampal dentate gyrus (DG) from a mouse model of early Alzheimer's disease. These AD mice exhibit severe β-amyloid plaques (red) in the DG at 9-months of age. Using these mice combined with a novel viral strategy, memory engram cells (green) for a contextual fear memory were labeled.

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RIKEN

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