Biosensing (IMAGE) Optica Caption One UV photon is absorbed by the antibody and the disulfide bridge is opened, thereby forming thiol groups. Their interaction with the gold surface leads to an oriented Fab region so that the upside down position (circled in the right side of the picture) is hampered and the antigen binding is more effective. Credit <I>Biomedical Optics Express</I> Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.