The Enzyme PpnN Binds pppGpp (IMAGE)

Aarhus University

The Enzyme PpnN Binds pppGpp

Caption

The figure shows how the enzyme PpnN binds pppGpp and speeds up conversion of guanylate (GMP) to its constituents ribose-5-phosphate and guanine. This enables bacteria to balance their tolerance towards antibiotics with the fitness requirements for survival (below).

Credit

Ditlev E. Brodersen/AU

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