Engineering of glycolyl-CoA carboxylase (IMAGE) Max-Planck-Gesellschaft Caption Engineering of glycolyl-CoA carboxylase (GCC), the key enzyme of the TaCo pathway. GCC was developed on the scaffold of a naturally occurring propionyl-CoA carboxylase (WT). Rational design led to the 50-times improved version M3, and additional high-throughput screening enabled the identification of a 900-fold improved version (M5). Credit Max Planck Institute for Terrestrial Microbiology/Scheffen Usage Restrictions Use of images is limited to editorial coverage of scientific topics relating to the activities of the Max Planck Society. Any kind of commercial use (including, in particular, the exploitation of images by means of sale or incorporation in image databases or image catalogues) as well as any promotional use/use for merchandise purposes, disclosure to third parties or granting of related rights to third parties is expressly not permitted. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.