Gut Microbes Protect against Sepsis (IMAGE)
Caption
This visual abstract depicts the findings of Wilmore et al., who demonstrate a role for serum IgA in protection against polymicrobial sepsis. Induction of protective concentrations of T cell dependent serum IgA requires colonization of the gut with a complex microbiota that includes bacteria in the phylum Proteobacteria.
Credit
Wilmore et al./Cell Host & Microbe 2018
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