CRISPR-Gold (IMAGE)

University of California - Berkeley

CRISPR-Gold

Caption

CRISPR-Gold is composed of 15 nanometer gold nanoparticles that are conjugated to thiol-modified oligonucleotides (DNA-Thiol), which are hybridized with single-stranded donor DNA and subsequently complexed with Cas9 and encapsulated by a polymer that disrupts the endosome of the cell.

Credit

Murthy/Conboy/Nature Biomedical Engineering

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