PMSE Brain (IMAGE) University of Pennsylvania School of Medicine Caption A PMSE brain exhibits abnormal brain architecture. On the left is a region of the cerebral cortex obtained post-mortem from a PMSE patient. The inset depicts neurons trapped in the white matter that have failed to move into the cortex during brain development. On the right are three examples of abnormally large neurons in the cerebral cortex in PMSE. Credit Peter B. Crino, M.D., Ph.D., University of Pennsylvania School of Medicine Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.