Regulation of Protein-Ligand Binding Affinity by Hydrogen Bond Pairing (IMAGE)

American Association for the Advancement of Science (AAAS)

Regulation of Protein-Ligand Binding Affinity by Hydrogen Bond Pairing

Caption

The mechanism of how synergistic H-bonds potentiate ligand binding to a receptor is shown. This material relates to a paper that appeared in the March 25, 2016 issue of Science, published by AAAS. The paper, by D. Chen at Gannan Normal University in Ganzhou, China, and colleagues was titled, "Boundary lubrication of heterogeneous surfaces and the onset of cavitation in frictional contacts."

Credit

Baylor College of Medicine

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