Figure 1 (IMAGE)
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(A) Cartoon depiction of chromatin packaged into compact heterochromatin and loosely packed euchromatin. (B) The segregation of heterochromatin and euchromatin is mediated by liquid-liquid phase separation with linker histone H1. (C) Two-color fluorescent microscopy images of histone H1 and HP1α (a heterochromatin marker protein) showing co-localization of H1 and heterochromatin in liquid-like droplets within HeLa nuclei.
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