Figure 1 (IMAGE) Institute for Basic Science Caption (A) Cartoon depiction of chromatin packaged into compact heterochromatin and loosely packed euchromatin. (B) The segregation of heterochromatin and euchromatin is mediated by liquid-liquid phase separation with linker histone H1. (C) Two-color fluorescent microscopy images of histone H1 and HP1α (a heterochromatin marker protein) showing co-localization of H1 and heterochromatin in liquid-like droplets within HeLa nuclei. Credit IBS Usage Restrictions Please indicate the credit License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.